Dear Colleagues, Friends, Sponsors, and Exhibitors,
We heartily welcome you with honor and pleasure to attend and participate in the upcoming 3rd International Conference on Pharmaceutics and Advanced Drug Delivery Systems (Pharmaceutical Science 2020) of the AAC for the Study of Pharmaceutics and Health care to be held on February 05-06, 2020 in Paris, France.
Pharmaceutical Science 2020 has become the premier platform not only for the presentation of new science but also for unique networking opportunities.
With delegates from more than 100 countries around the world attending this Pharmaceutical Science Conference, so it will provide an ideal platform to discuss recent discoveries.
And the main theme of the Pharmaceutical Science conference will be “Future Outlook & Rising Applications of Pharmaceutics & Drugs’’.
It will be great forum for the participants to explore the cutting-edge research and development in health care sectors.
We look forward to welcoming you to an exciting, enlightening, educational and enjoyable program in Paris, France.
Organizing Committee | Pharmaceutical Science 2020
Pharmaceutical Science 2020, thrives to gather like minded people from various disciplines of Pharmaceutical and Health care Sectors in a single forum.
l Exploit chances to learn about pharmaceutics and drugs and look into an assortment of oral and poster presentations.
l Encounter and connect with pharmacists ranging from students to deans, faculty, and research scholars.
l Join outstanding plenary sessions about important issues affecting pharmaceutics and related science.
Benefits of Participation at Pharmaceutical Science 2020:
l Acknowledged abstracts will be published in the Journal of Clinical Research and Pharmacy provided with unique DOI number
l Global networking with the experts
Conference Opportunities for Researchers and Faculty Members:
l Speaker Presentations
l Poster Display
l Symposium Hosting (4-5Members Team)
Global Experts in Pharmaceutics
Health care Professionals
Pharmaceutics Research organizations, societies, and associations
In the spirit of science having no cultural bounds, come and join us to explore the new possibilities and ton of new ideas..!
Eagerly waiting to see you all in the conference at Paris, France.
Sessions and Tracks
Drug designing is one of the essential components for drug discovery process. Drug Screening predicts the binding energy of the lead molecule to the target & the thermodynamic properties. Molecular mechanics/Molecular dynamics is the most used methods to predict the model conformation changes
This session will discuss the practical difficulties in drug targeting and designing and approaches to overcome them.
Pharmacokinetic activity depends on the amount of drug levels at the target site . Recent advances in analytical and quantitative methodologies are often non-invasive assessments of drug pharmacokinetics at the site of action for better understanding of pharmacokinetic properties.
Pharmacodynamics is affected by various factors including receptor binding and sensitivity, post receptor effects, chemical interactions, physiologic changes due to genetic mutations, diseases, aging, or impact of other drugs. Pharmacodynamics and pharmacokinetics explain the effects of drugs to the host body.
Session on Pharmacogenomics
The effect and response of drug varies for each individual due to variations in genome for each individual. Pharmacogenomics helps to analyse genetic effect of individuals in response of particular drug and gene-drug interactions in body.
Pharmacogenomics is the basis of personalized medicines, a relatively new concept and expected to flourish in the future.
Pharmacology has evolved as a multi-disciplinary science with many sub-specialties including clinical pharmacology, cardiovascular pharmacology, behavioral pharmacology, neuropsychopharmacology, pharmacogenetics, and Pharmacoeconomics.
Pharmacology assess the positive effects of the drugs while toxicology deals with the negative effects of the drug as well as chemical substances and the means to ameliorate such effects.
Session on Pre-formulation & Formulation Aspects
The physio-chemical and mechanical properties of the drug are indispensable in the preparation of the drug in pre-formulation studies. In dealing with protein pre-formulation, it is important to consider the solution behaviour of a given protein under different physiological conditions.
While formulating the drug, physio-chemical properties like particle size, polymorphism`, pH and solubility are should be taken into consideration as they impact bio availability and the activity of a drug. The formulation should ensure that the dosage should have a uniform appearance, acceptable taste and capsule disintegration properties.
Clinical pharmacy and pharmacy practice play important roles in clinical trials and clinical research. In recent years pharmacist role in clinical research and patient care has improved significantly and they play active role in designing and modifying drug therapies. This session focuses on the recent advancements in clinical research and pharmacy practice.
Session on Pharmaceutical Technology
Pharmaceutical technology utilizes engineering and technology in different areas of pharmaceutical sector. It consists of methods, techniques, and handling of instruments in the formulation, manufacture, packaging, and logistics of drugs and other techniques used in diagnostic, determinative and medication procedures.
Pharmaceutical microbiology and biotechnology have evolved as a useful field for the productions of biologic from microbial cells or animal or human cell lines. Biotechnological concepts and manipulations in the these filed has enhanced the production, variety and types of biologic produced. These field are expected to grow further in the future.
Pharmaceutical and Medical chemistry are holistic scientific studies dealing with the interdisciplinary concepts that includes drug discovery, molecular mechanisms of pathogens, pharmaceutics, pharmacology, toxicology, organic chemistry and more.
Both fields as a whole provide better insights and understanding than individual studies towards the development of new drugs and therapeutics.
This session deals with various technological developments in Bio-therapy for Cancer treatment, Chemotherapy and Immunotherapy, Bio-therapy in wound treatment, Radio-pharmaceuticals and Nuclear medicine.
In recent years the research and development is focused much on innovative biologic and spurring the introduction and access to biosimilars. The FDA has issued several drafts and final guidance to assist biosimilar sponsors in generating data to support biosimilar applications. The FDA guidance and regulations provide insights regarding evaluation of biosimilars. The FDA is working to provide additional guidance on how biosimilar products could be designated to reference products. This session brings out the current, on-going researches and new regulations with respect to biologic and biosimilars.
Phytochemicals and herbal medicines possess certain limitations like instability at high acidic pH, first-pass metabolism in liver, poor solubility and absorption problems. With the help of novel drug delivery systems first-pass metabolism, degradation in gastrointestinal tract, accumulation of the drug at non-targeted tissues are minimized with plant derived drugs with reduced side effects and improved therapeutic efficacy.
This session deals with the major challenges in drug delivery systems such as delivery and bio-availability of poorly soluble drug compounds and inaccessibility of drug molecules to the target site. Other Major Challenges include biologic (peptides, proteins and DNA-based therapeutics) drug delivery, pediatric and geriatric drug delivery. Although certain strategies and approaches were developed to eliminate the problems in the drug delivery, they face certain shortcomings. With the help of new technologies it is possible to overcome such hurdles in drug delivery systems.
New technologies and approaches are being developed to overcome the challenges in drug delivery. They are smart drug delivery systems, sustained release drug delivery, nano particle-based drug delivery systems, medical devices for drug delivery, drug delivery system for biologic and printing technology in dosage forms. These new methods are collectively called as drug delivery systems (DDS), which are based on multidisciplinary approaches that combine pharmaceutics, bio conjugate chemistry, molecular biology, pharmacology, polymer sciences, nanotechnology and electronics. A successful drug delivery system is the key for successful treatment of a diseases.
Session on Pharmaceutical Nanotechnology
Pharmaceutical nanotechnology offers innovative tools and technology, opportunities and scope in many areas of healthcare sector and it is now well-established as specialized area for drug delivery, diagnostics, prognostic and various treatment procedures through its nano-engineered tools and techniques.
It has a great impact in the future by overcoming the limitations of current technology in pharmaceutical sector.
Session on Novel Drug Delivery System
The main advantage of novel drug delivery system is providing the drug to the target site in a controlled manner for enhanced efficacy with less side effects. It follows two approaches one is spatial drug delivery which involves targeting a drug to a particular organ or tissue and another one is temporal drug delivery. In this the rate of the drug delivery to the target tissue is controlled by various techniques.
Session on Targeted Drug delivery system
The significance of targeted drug delivery is the selective delivery of pharmacologically active agent to the targeted site of action and no effect on non-targeted tissue or organ. This is particularly useful in treatments such as cancer chemotherapy and enzyme substitute treatment. It utilizes techniques such as Niosomes, Resealed Erythrocytes, Micro-spheres, Monoclonal antibodies, Liposomes, Magnetic micro-particles to achieve the targeted drug delivery.
Session on Alternative Drug Delivery Systems
Oral drug delivery system and parental drug delivery system are the most commonly used drug delivery systems. This session will focus on alternative drug delivery methods such as pulmonary drug delivery, trans-dermal drug delivery, pro-drug delivery, ocular drug delivery and transmucosal drug delivery.
This session deals with challenges in various types and routes of peptide and protein drug delivery, Vaccine design and drug delivery, Recent advanced in protein-based drug delivery and solutions to overcome the potential drug delivery-based barriers.
The USFDA has set more stringent compliance parameters and price regulations to ensure the quality assurance of pharmaceutical products and welfare of public health. In addition to CGMP, GLP and GCP as per the US Federal law pharma products should comply with 21CFR regulations.
The FDA also organizes compliance programs for the pharma industries in program areas like Food and Cosmetics (CFSAN), Drugs (CDER), Devices/Radiological Health (CDRH), Biologic (CBER), Bio research Monitoring (BIMO), Veterinary Medicine (CVM) in a regular basis.
With the rapid development of new drug and innovative therapeutics, new pharmacovigilance procedures and methods have to be implemented for assurance of drug safety and the quality of life of patients.
Pharmaceuticals in one of the main and essential field for the welfare of human society and it is also one of the largest in the global economy. The total value of the pharmaceutical sector is over $5 trillion. It is one thousand-fold more when compared to what is was in the 1920s. Moreover, the pharmaceutical industry is likely to triple in size in by 2060 and the pharmaceutical industry is around 30% larger than previously thought and is one of top five in the global economy.
The total market value of drug delivery technology is estimated to reach USD 1,669.40 Billion by 2021 from USD 1,179.20 Billion in 2016, at a CAGR of 7.2% during the forecast period.
As illustrated in the graph the worldwide prescription drug sales is $774 billion in 2017 and $811 in 2018. The prescription drug sales revenues are expected to reach over one trillion U.S. dollars by 2022. There is an increasing growth in sales of biological products as well. Pharma market areas such as Generic drugs, Rare disease therapeutics, Active pharmaceutical ingredients (API) are rapidly growing. Packaging and logistics also growing along with the main pharma market.
Current market scenario in pharma sector:
The Pharma market nowadays is dramatically changing due to new innovative research and demand for new therapeutics and new regulatory policies and requirements. There is an increasing demand for generic drugs from countries such as Russia, UK, USA, China and India in recent years and developing drugs for the rare disease has become increasingly mainstream. Because of high market value and comparatively low development costs, this area has a considerable investment. Rare disease therapeutics companies have a become an important growing part of the pharmaceutical marketplace.
According to an estimate performed in October 2017, the total market value of the top 20 rare disease non-oncology companies was about $315 billion and for rare disease oncology companies was about $193 billion. Many oncology-based companies have proceeded rare forms of cancer for approvals. And now, the rare disease market segment is more than a half trillion in value. So, a Continued Growth in Rare Disease Sector is expected in the future. For Active Pharmaceutical Ingredients (API), in terms of geographic regions the market research and analysis estimate that, France will be one of the major revenue contributors to the API market throughout the next four years.
And certain pharmaceutical companies are now focusing on developing new innovative therapeutics such as peptide therapeutics, Nucleic acid therapeutics and cell therapy. Specifically, a new field of research, Bio-electronics & Electroceuticals. All these innovative approaches will create a revolution in the pharma sector.
Key players in the pharma market:
UK is one of the predominantly dominating countries in pharma sector in most of the aspects. With respect to investments for R&D in pharmaceutical sector UK plays a key role globally.
Other key players include USA, China, Japan, Germany, and Russia.
Future projections about pharma sector:
The total revenue of the pharmaceutical industry is expected to triple in real terms between 2017 and 2060.
Certain markets would see outsize growth. For example, the size of the China pharma sector would grow fourfold between now and 2060 while the European market would grow more slowly.
The rare disease sector will be an important growth driver in the pharmaceutical industry.
New innovations will improve the size and growth of the pharma sector with positive implications for the health and welfare of the society.
It is expected that the long-term growth will be driven by new therapeutics such as nucleic acids therapeutics and implantable.
It also appears likely that the fields of cell therapy and regenerative medicine will see numerous approvals in the decades ahead.
Paris is among the three most important and influential cities in the world. Also, one of the most visited cities in the world and among the top 10 cities to live in. It is one of the largest inter-modal ports in the world and a major transportation hub in France. Paris is a global city, a thriving center of international trade and commerce, and a place where people of every nationality come to pursue their career.With respect to Research and Development, Paris is one of the major centres in the word. The Greater Paris Region is a leader in terms of R&D accounting for 7.5% of European expenditure on R&D on a European level.
Besides, this is a city to be toured, The River Seine-is is a socializing hotspot with jaw dropping city and river views. Disneyland Paris is for the kid in all of us. At world renowned Luxembourg Gardens, capture the perfect selfie at the tree-lined promenades, and revel in the virtual reality of Medici Fountain. Visit Louvre Museum, the world’s most visited museum, housing a collection of more than 1 million objects. Take a tour at the Champs-Elysee, Paris’s most famous street and has even been described as the most beautiful avenue in the world. Gasp at the Palace of Versailles with magnificent gardens and the Hall of Mirrors, Finally, visit the iconic symbol of Paris, one of the most photographed tourist attractions in the world, and much more to explore.
R&D in Paris:
France’s leading R&D center with 100,000 researchers
The Greater Paris Region is a major center for French Research and Development and is the focus of over 40% of both R&D expenditure and staff. In 2011, €18.4 billion was
spent on R&D in the Greater Paris Region, two thirds of which came from businesses. The total number of jobs in R&D stood at 150,000 including 100,000 researchers.In order to maintain and stimulate this regional strength, various initiatives have been undertaken by the State and the region:
The creation of the “Credit d’Impôt Recherche” (CIR – Research tax credit) which aims to encourage Research and Development by allowing businesses to reduce their tax
liabilities in line with their expenditure on R&D (experimental research, applied research and experimental development). This tax credit reduces the amount of Corporation
Tax owed by a company and can account for up to 30% of annual expenditure on R&D.Establishment of “Clusters” dedicated to Research Technologies, in order to stimulate
Research and encourage collaboration between public and private establishments. Various competitiveness centres have been established in the Greater Paris Region. Particularly worthy of note among the major centres is one in Sac-lay which is dedicated to new technologies and a health and bio-technology center to the South of the region between Villejuif and Evry.
The CIR scheme is considered as very attractive for R&D investment (linked to the presence of major groups, innovative SMEs and SMIs public laboratories and student researchers) and aims to create a favorable business environment which should allow Paris to continue as a global center for Research over the coming years