Pharmacokinetics and Drug Interactions

Pharmacokinetics and Drug Interactions Photo

Pharmacological activity depends on adequate drug levels at the effect site, but access to these sites for pharmacokinetic sampling is often limited. Thus, we often rely on plasma concentrations as surrogates in efforts to understand exposure–response relationships. Recent advances in analytical and quantitative methodologies allow for more robust and often non-invasive assessments of drug pharmacokinetics at the site of action for better understanding of pharmacokinetic properties.

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